For MS Victims
dailyhealth@electricmessage.co.uk
11 Oct 2007
http://www.electricmessage.co.uk/hsi
Dear Reader,
According to the latest research findings high doses of up to 280,000
international units (IU) of vitamin D3 per week appear to be safe to
administer to multiple sclerosis (MS) patients.
Vitamin D has been found to be reduced in the blood of individuals
suffering from the disease, and raising levels by administering the
vitamin may prove to be beneficial.
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Assessing the results
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Researcher, Samantha M Kimball of the University of Toronto and her
colleagues gave twelve men and women in the active stage of MS 1,200
milligrams of calcium per day and a weekly dose of vitamin D that was
increased over six visits from 28,000 IU at the beginning of the study
to 280,000 IU at the end of 28 weeks.
Serum 25-hydroxyvitamin D, calcium, parathyroid hormone, liver enzymes
and creatinine levels (which assess kidney function), as well as
urinary calcium and creatinine were measured at the beginning of the
study, at each patient visit, and three months after the end of the
treatment period.
Although the participants' serum concentrations of 25-hydroxyvitamin D
rose to double the top of the normal range by the end of the study,
serum calcium levels and urinary calcium to creatinine did not increase
or exceed safe levels. In addition, disease progression and activity
did not appear to be affected by vitamin D treatment, yet the brain
lesions that are characteristic of the disease were reduced from an
average of 1.75 per patient to 0.83.
The researchers concluded that: "The widespread use of vitamin D
supplements (1000 IU)/d) has been advised as a simple way to improve
many aspects of public health. The present study provides an objective
confirmation that the recent proposal by Hathcock et al is appropriate
i.e., an upper limit of 250 micrograms/day (10 000 IU/d) for vitamin D
intake can be justified."
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